URI permanente desta comunidadehttps://repositorio.fmc-campos.com.br/handle/123456789/31
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Item Impacto da interação fármaco-alimento na eficácia do trata mento de doenças da comunidade(2025-06-26) Yasmin Moraes Gomes de Almeida; Laidy Vittória Acien Pereira; Maycon Bruno de AlmeidaDrug interactions occur when the effects of a drug are altered by another drug or food, and may be physicochemical, pharmacokinetic or pharmacodynamic. Drug-food interactions involve cytochrome P450 enzymes and P-glycoprotein, impacting the efficacy and safety of the treatment of diseases in the community. Foods such as grapefruit, dairy products and alcohol can modify the effects of antihypertensives, antidepressants, NSAIDs and anticoagulants, among others. Drug-drug interactions (DDIs) account for 26% of adverse events, increasing hospitalizations. Of the 1658 articles found in PubMed, 40 were selected, highlighting that food can interfere with the efficacy and safety of antihypertensives, antidepressants, NSAIDs and anticoagulants, increasing the risk of toxicity and decreasing absorption, demonstrating the importance of considering diet when prescribing medications to optimize treatment efficacy and minimize risks. Training healthcare professionals is crucial to ensuring safe and effective treatment in the community