Choque séptico de origem pulmonar por Acinetobacter baumannii multirresistente em paciente imunocompro metido: relato de caso

Abstract

Infections caused by Acinetobacter baumannii represent a growing challenge for healthcare services, especially in hospital settings, due to their resistance to antibiotics. This report addresses the therapeutic management of a severe infection caused by multidrug resistant A. baumannii in a patient admitted to an intensive care unit (ICU) A 42-year old man was admitted to the ICU with respiratory distress and fever. Examinations revealed a severe pulmonary infection, associated with other complications. The patient was empirically treated with polymyxin B and fluconazole, and subsequently with meropenem and linezolid. Following initial antimicrobial therapy, cultures were performed confirming the presence of multidrug-resistant A. baumannii. The antibiogram revealed resistance to several antibiotics, except for tigecycline. The conduct was adjusted based on culture results. Managing infections caused by multidrug-resistant A. baumannii is challenging due to the limited efficacy of available antibiotics. Tigecyclin has shown effectiveness against multidrug-resistant strains, however, closely monitoring treatment response and considering therapeutic changes when necessary is essential.