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Item Therapeutic strategies carried out in cases of a metronidazole-re sistant Trichomonas vaginalis infection: a literature review(2023-12-24) Yasmim de Souza Leite; Laís Verdan DibTrichomoniasis is the most prevalent non-viral sexually transmitted infection worldwide, caused by Trichomonasvaginalis. This parasitic infection primarily affects women, who may experience clinical manifestations such as leukorrhea, unpleasant vaginal odor, vulvar itching, and a strawberry cervix. While metronidazole is the drug of choice for treating this infection, strains of T. vaginalis resistant to this medication have been increasingly reported globally. In this context, the objective of this study was to conduct a literature review of reported case studies involving alternative therapeutic regimens used for metronidazole-resistant T. vaginalis strains, published up to the year 2019.The databases used were PubMed and the Scientific Electronic Library Online (SCIELO). Scientific articles that were fully available online and provided detailed information on alternative treatment approaches for metronidazole-resistant T. vaginalis infections were included. Systematic reviews, master’s dissertations, and doctoral theses published up to 2019 were excluded. Results: A comprehensive analysis of 16 scientific articles was conducted, yielding 23 clinical cases. Regarding therapeutic regimens, tinidazole was the most commonly used drug for cases of metronidazole-resistant strains, followed by paromomycin and iodopovidone. No standardized therapeutic guidelines were observed among healthcare professionals in cases of metronidazole-resistant T. vaginalis infections based on the analyzed reports.Item Esquemas terapêuticos realizados em casos de infecção por Tri chomonas vaginalis resistentes a metronidazol: uma revisão bi bliográfica(2024-12-23) Yasmim de Souza Leite; Laís Verdan DibTrichomoniasis is the most prevalent non-viral sexually transmitted infection worldwide, caused by Trichomonasvaginalis. This parasitic infection primarily affects women, who may experience clinical manifestations such as leukorrhea, unpleasant vaginal odor, vulvar itching, and a cervix resembling a strawberry. While metronidazole is the drug of choice for treating this infection, strains of T. vaginalis resistant to this medication have been increasingly reported globally. In this context, the objective of this study was to conduct a literature review of reported case studies involving alternative therapeutic regimens used for metronidazole-resistant T. vaginalis strains, published up to the year 2019.The databases used were PubMed and the Scientific Electronic Library Online (SCIELO). Scientific articles that were fully available online and provided detailed information on alternative treatment approaches for metronidazole-resistant T. vaginalis infections were included. Systematic reviews, master’s dissertations, and doctoral theses published up to 2019 were excluded. Results: A comprehensive analysis of 16 scientif ic articles was conducted, yielding 23 clinical cases. Regarding therapeutic regimens, tinidazole was the most commonly used drug for cases of metronidazole-resistant strains, followed by paromomycin and iodopovidone. No standardized therapeutic guidelines were observed among healthcare professionals in cases of metronidazole-resistant T. vaginalis infections based on the analyzed reports.Coleção Coleção Coleção