Medicina

URI permanente para esta coleçãohttps://repositorio.fmc-campos.com.br/handle/123456789/40

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    Esquemas terapêuticos realizados em casos de infecção por Tri chomonas vaginalis resistentes a metronidazol: uma revisão bi bliográfica
    (2024-12-23) Yasmim de Souza Leite; Laís Verdan Dib
    Trichomoniasis is the most prevalent non-viral sexually transmitted infection worldwide, caused by Trichomonasvaginalis. This parasitic infection primarily affects women, who may experience clinical manifestations such as leukorrhea, unpleasant vaginal odor, vulvar itching, and a cervix resembling a strawberry. While metronidazole is the drug of choice for treating this infection, strains of T. vaginalis resistant to this medication have been increasingly reported globally. In this context, the objective of this study was to conduct a literature review of reported case studies involving alternative therapeutic regimens used for metronidazole-resistant T. vaginalis strains, published up to the year 2019.The databases used were PubMed and the Scientific Electronic Library Online (SCIELO). Scientific articles that were fully available online and provided detailed information on alternative treatment approaches for metronidazole-resistant T. vaginalis infections were included. Systematic reviews, master’s dissertations, and doctoral theses published up to 2019 were excluded. Results: A comprehensive analysis of 16 scientif ic articles was conducted, yielding 23 clinical cases. Regarding therapeutic regimens, tinidazole was the most commonly used drug for cases of metronidazole-resistant strains, followed by paromomycin and iodopovidone. No standardized therapeutic guidelines were observed among healthcare professionals in cases of metronidazole-resistant T. vaginalis infections based on the analyzed reports.
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    Knowledge and behavior towards COVID-19 in the northern region of the state of Rio de Janeiro – Brazil
    (2024-02-19) Thais Louvain de Souza; Andre L Vargas; Larissa PV Souza; Lauryne MBR Paes; Raleigh P Dias; Thiago F Marotti; Inez Barcellos de Andrade
    Abstract Introduction: Despite efforts by health organizations to share evidence-based information, fake news hindered the promotion of social distancing and vaccination during the coronavirus disease 2019 (COVID-19) pandemic. This study analyzed COVID-19 knowledge and practices in a vulnerable area in northern Rio de Janeiro, acknowledging the influence of the complex social and economic landscape on public health perceptions. Methodology: This cross-sectional study was conducted in Novo Eldorado – a low-income, conflict-affected neighborhood in Campos dos Goytacazes – using a structured questionnaire, following the peak of COVID-19 deaths in Brazil (July–December 2021). Statistical tests were used to delineate profiles and evaluate knowledge and preventive behaviors associated with COVID-19. Results: This study involved a cohort of 156 participants, predominantly women (74%), with an average age of 53 years. Almost half of the participants were identified as single (48%), and more than half had not completed elementary school. Notably, 68% believed they were well informed about COVID-19. The answers to the questionnaire revealed that the majority correctly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a virus (65%); 72% recognized fever or cough as the main symptoms; and 71% recognized the importance of wearing masks. The overall mean score of the study was 7.628 (SD 1.583047). Social networks, especially ‘WhatsApp’ (65%), were the primary information sources. Those using social media or WhatsApp had higher knowledge scores (8.000 vs. 7.000, p = 0.0064). Conclusions: Involving marginalized communities and using social media to disseminate accurate information and trust in science is necessary to tackle COVID-19 challenges.
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    Therapeutic strategies carried out in cases of a metronidazole-re sistant Trichomonas vaginalis infection: a literature review
    (2023-12-24) Yasmim de Souza Leite; Laís Verdan Dib
    Trichomoniasis is the most prevalent non-viral sexually transmitted infection worldwide, caused by Trichomonasvaginalis. This parasitic infection primarily affects women, who may experience clinical manifestations such as leukorrhea, unpleasant vaginal odor, vulvar itching, and a strawberry cervix. While metronidazole is the drug of choice for treating this infection, strains of T. vaginalis resistant to this medication have been increasingly reported globally. In this context, the objective of this study was to conduct a literature review of reported case studies involving alternative therapeutic regimens used for metronidazole-resistant T. vaginalis strains, published up to the year 2019.The databases used were PubMed and the Scientific Electronic Library Online (SCIELO). Scientific articles that were fully available online and provided detailed information on alternative treatment approaches for metronidazole-resistant T. vaginalis infections were included. Systematic reviews, master’s dissertations, and doctoral theses published up to 2019 were excluded. Results: A comprehensive analysis of 16 scientific articles was conducted, yielding 23 clinical cases. Regarding therapeutic regimens, tinidazole was the most commonly used drug for cases of metronidazole-resistant strains, followed by paromomycin and iodopovidone. No standardized therapeutic guidelines were observed among healthcare professionals in cases of metronidazole-resistant T. vaginalis infections based on the analyzed reports.